Fecal incontinence often occurs after childbirth, abdominal surgery and radiotherapy. Elderly and chronic constipation are also prone to fecal incontinence due to anal sphincter injury and dysfunction. It not only causes inconvenience in life, affects the quality of life, but also causes great psychological trauma.
Dajianzhong Decoction is a classic prescription in “The Synopsis of the Golden Chamber”. It is composed of ginseng, Sichuan pepper, dried ginger, and caramel. It is a classic strong analgesic. It has anti-inflammatory, anti-tumor, and improves intestinal microcirculation. Peristalsis and intestinal anastomosis healing and regulating intestinal flora. It is suitable for cold pain and bloating of the abdominal abdomen. In modern times, it is mostly used for the protection of gastrointestinal function after abdominal surgery. The prevention and treatment of postoperative intestinal obstruction by Dajianzhong Decoction has been a research hotspot in recent years.
The “zhong” of Dajianzhong soup “build” is mainly the small intestine and large intestine. In addition, there are many applications in reflux esophagitis and chronic gastritis. As the last pass of the digestive tract, Dajianzhong Decoction also has “constructive significance” for the anus. Previous studies have found that Dajianzhong Decoction can lower the gastrointestinal sensory threshold, increase the tension of the internal and external anal sphincter, and treat chronic constipation.
A recent study found that Dajianzhong Decoction can be used to treat fecal incontinence. A single-center retrospective observational study in Japan included 157 patients with fecal incontinence. Considering patients with anal sphincter dysfunction, they took Dajianzhongtang granules (7.5 grams per day) for one month, and found that Dajianzhongtang significantly improved fecal incontinence. It significantly reduces the use of diapers and improves the fecal incontinence score; there is no significant improvement in the chronic constipation score, but it significantly reduces the dependence on other auxiliary laxative measures, and Dajianzhong soup can make the stool more shape. , Increase anal tension and defecation strength. No drug-related adverse reactions were observed.
Therefore, it can be considered that the scope of action of Dajianzhong soup covers the entire passage from the esophagus to the anus.
AbeT, Kunimoto M, Hachiro Y, Ohara K, Murakami M. Clinical efficacy of Japaneseherbal medicine daikenchuto in the management of fecal incontinence: A single-center,observational study. J Anus Rectum Colon. 2019 Oct 30;3(4):160 -166. doi: 10.23922/jarc.2019-012. PMID: 31768466; PMCID: PMC6845288.
AbeT, Kunimoto M, Hachiro Y, Ohara K, Murakami M. Clinical efficacy of Japaneseherbal medicine daikenchuto in the management of fecal incontinence: A single-center,observational study. J Anus Rectum Colon. 2019 Oct 30;3(4):160-166. doi: 10.23922/jarc.2019-012. PMID:31768466; PMCID: PMC6845288.